Genetics

No hair in the hairless dogs (except naked American terrier - american hairless terrier) is the result of an incomplete dominant mutation that is lethal in homozygot.Dr. O'Brien team found the gene 'nagości'u chinese crested in chromosome 17 on the occasion of research on neurological disease called. PNA (PNA - Progressive Neuronal Abiotrophy) (Source p.41) The name comes from the Latin lethal letalis - śmiertelny.Letalnymi called genes or genotypes, which results in the inability to life and death of the individual prior to the maturity. Lethal genes arise from mutations (gene or chromosome) that prevent the normal development of a carrier as a result of his lack of ability to syntezyjednego or more of the essential enzymes. When it can be said that the gene is lethal? Some genes affect the phenotype of the dog, reducing its chances of survival. Genes may interact and cause death shortly after fertilization. Others may prevent further development at the stage of blasts (microscopic balls of cells). Yet others may not appear until the embryo is not formed in full .. Many lethal genes causes death shortly after birth because they prevent the normal functioning of the lungs, kidneys and heart.
Each naked crested carries the dominant lethal gene 'no hair' (Hr) and the gene 'normal type of hair'(hr). Gene (Hr) is dominant over the gene (hr) in the formhomozygotes (hrhr) causes the death of the fetus. Genotype naked dog is as follows: (hrhr).
Hrhr rys.K.Zienkiewicz
Puppies honozygotyczne in terms of gene 'no hair' (Hr) with genotype (hrhr) are not born. Die in the womb and are reabsorbed by the body.
HrHrRys. K.Zienkiewicz
Poowder puffy have nudity gene (Hr), only a few genes are 'normal hair' (hr), the genotype is as follows: (hrhr). Such a combination is in no way is lethal.
hrhrRys. K.Zienkiewicz
                          Crosswords:
Rys.© Katarzyna Zienkiewicz

Crossword two naked dogs (hrhr) x (hrhr) could theoretically result in the following combinations: 1 (hrhr) (25%) - homozygous nude dog - killed, 2 (hrhr) (50%) - heterozygous naked dogs - survive; 1 (hrhr) (25%) - homozygous for the normal type of dog hair - is experiencing. However, in practice, such a combination can provide the same or nude hairy puppies or any combination thereof.
Rys.© Katarzyna Zienkiewicz

Crossword naked dog Powder Puff theoretically gives the following result: 2 (hrhr) (50%) - heterozygous naked dogs - survive; 2 (hrhr) (50%) - homozygous dogs with normal type of hair - przeżywają.Jednak in practice, such a connection can give the same hairy or bare puppies or any combination thereof.
Rys.© Katarzyna Zienkiewicz

Crossword two puffów powder gives the result: 4 (hrhr) (100%) - homozygous dogs normalnymtypie hair - are going through.
Prepared by: Katarzyna  Zienkiewicz Kennel Rosa Thea.
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